Foundation for Women’s Health Promotion and Welfare Initiatives

FWHPWI

We can still do more to reduce

Ovarian Cancer deaths and

Suffering

FWHPWI 2022 March

Meeting/Outreach

Preclinical Study Identifies New

Target for Recurrent Ovarian

Cancer

Researchers now have improved

understanding of a rare ovarian

tumor

New study turns cancer cells

into immune cells to attack the

cancer the cells come from

Researchers have found that

remnants of ancient retroviruses

passed down in our DNA could

be an effective target for

antibodies against lung cancer

Discovery of anti-cancer

chemistry makes skullcap fit for

modern medicine

A New sustainable source for a

promising cancer killer

New global funding opportunity

for Cancer Research

WHO-AFRO: Early detection

remains key in cervical cancer

elimination

First African-produced cancer

tests to slash costs and waiting

times

The current situation of cancer

care in Africa?

Lifestyle changes may prevent

nearly half of the world’s cancer

deaths

Adherence to healthy lifestyle

found to cut breast cancer

recurrence/mortality

Natural Source of Selenium as

Functional Food Products for

Chemoprevention

How Do Diet and Exercise Help

Prevent Cancer?

Make whole grains, vegetables,

fruits and pulses (legumes) such

as beans and lentils a major

source of your normal diet

Benefits of good nutrition

during cancer treatment

According to researchers,

cooking sweet corn boosts its

ability to fight cancer and heart

disease by freeing healthful

compounds

Ovarian cancer can be described as a group

of diseases that originate in the ovaries, or

in the related areas of the fallopian tubes

and the peritoneum.

Several factors have

been discovered by studies and highlighted

by experts as the factors that may increase

a woman’s risk for ovarian cancer; examples

are:

A) being middle-aged or older

B) being overweight or obese

C) having children later or never having

a full-term pregnancy

D) taking hormone therapy after meno-

pause

E) having a family history of ovarian

cancer, breast cancer, or colorectal

cancer

F) having a family cancer syndrome

- resulting from inherited changes

(mutations) in certain genes

G) using fertility treatment

H) having had breast cancer

I) smoking.

Notwithstanding these many risk factors,

ovarian cancer presents a markedly

worrying reality – which is the fact that the

exact cause of the disease is not

known. Most women get the disease

without being at high risk of the known

factors. Yet, we must add to this hard

reality, the fact of increasing prevalence of

the disease. The estimate is that from 2020

statistics, by 2040, the number of women

around the world diagnosed with ovarian

cancer will rise almost 42%, and the

number of women dying from ovarian

cancer each year is projected to increase by

over 50%.

It is no exaggeration to say that the

cancer each year is projected to increase by

over 50%.

Yes, it is no exaggeration to say that the

situation is alarming. But the big event of

May 8, World Ovarian Cancer Day took

place this month of May 2023, as it has

always since 2013 when it was launched,

thanks to the noble initiatives of a group of

leaders from ovarian cancer advocacy

organizations around the world.

The theme for this year is "No Woman Left

Behind". This calls for a long awareness

campaign that aims to highlight the

importance of screening, recognizing

symptoms, and early diagnosis, particularly

among women in underdeveloped and

middle-income countries. Therefore, we at

FWHPWI encourage every woman to get

involved in the fight against ovarian

cancer. Yes, we can still do more – by

everyone getting involved in their own

capacity, to keep the campaign role on, day

after day, creating awareness of the already

known ovarian cancer risk factors, and also

helping to prevent the preventable by

motivating possible healthy lifestyle

against the disease.

Page 1

Dr. F. N. Alaribe Nnadozie,

(MD, FWHPWI)

1. Center for Disease Control and Prevention (CDC), USA

2. American Cancer Society

3. World Ovarian Cancer Coalition

On our March outreach, Nurse Ann

Okorie showcased blood pressure test, and

highlights on abnormal blood pressure.

Dr. F.N. Alaribe Nnadozie discussed current

liver detox herbs and the need to evaluate

their suitability for detoxing.

Below are some examples of

Liver Detox Herbs

Dr. Alaribe Nnadozie highlighted further

readings that could be of interest to those

who want to know more about detox herbs.

She also highlighted the importance of only

scientifically recognized, evaluated, and

standardized herbs and urged one to always

seek doctors' advice before embarking on

Ovarian cancer

is not a silent killer

- recognizing its

symptoms could

help reduce

misdiagnosis and

late detection

Page 2

Research News

Preclinical Study Identifies New

Target for Recurrent Ovarian Cancer

Results from a preclinical study, led by

researchers from the Perelman School of

Medicine at the University of

Pennsylvania, verified a new target for

drug-resistant ovarian cancer and provided

data to examine its utility as a target for

antibody-drug conjugates.

Click to join us

share information about the cancers

MILK THISTLE

Image credit: https://livingseed.co.za

She also highlighted the importance of only

scientifically recognized, evaluated, and

standardized herbs and urged one to always

seek doctors' advice before embarking on

any treatment with herbs, especially when

one is on medication.

Some FWHPWI

participants on the occasion

FWHPWI

TUMERIC & CURCUMINE

Image credit: https://gardenerspath.com

DANDELION

Image credit: https://stock.adobe.com

Researchers now have improved un-

derstanding of a rare ovarian tumor

Ovarian granulosa cell tumor is a rare type

of ovarian cancer that affects the ovaries

and fallopian tubes, and can extend further

into the pelvis and lymph nodes.

Researchers at Hokkaido University have

analyzed the disease and treatment of

hundreds of women with ovarian granulosa

cell tumors and say more invasive surgery

could be avoided in some cases. The find-

ings, published in the journal -Gynecologic

Oncology, improve understanding of how the

disease progresses and responds to therapy.

New study turns cancer cells into

immune cells to attack the cancer the

cells come from

Some cities fight gangs with ex-members

who educate kids and starve gangs of new

recruits. Stanford Medicine researchers

have done something similar with cancer –

altering cancer cells so that they teach the

body’s immune system to fight the very

cancer the cells came from. This is said to be

a discovery that could open up an entirely

new therapeutic approach to treating

cancer.

Researchers have found that remnants

of ancient retroviruses passed down in

our DNA could be an effective target

for antibodies against lung cancer

The research part-funded by Cancer

Research UK, could further our under-

standing of different patient responses to

immunotherapy treatments and also

improve these treatments for the future.

Discovery of anti-cancer chemistry

makes skullcap fit for modern

medicine

The Skullcap genus has been used for

centuries in Traditional Chinese Medicine

for treatment of different medical

conditions. Clinical work has shown that

preparations based on Scutellaria barb-

ata (the barbed skullcap) during

chemotherapy can reduce the risk of

metastatic tumors.

Page 3

Just a few ways to

reduce your risk of

gynaecological cancers

advised by

National Foundation

for Cancer Research

Have your Pap test

by age 21

The Pap test looks for abnormal

cell changes in the cervix to

detect cervical cancer in its early

stages.

Protect yourself from

Human papilloma

virus (HPV)

Talk to your doctor about

getting the HPV test and HPV

vaccine. Also, limit your sexual

partners and, when you do have

sex, use a condom.

Don’t smoke.

Smoking increases the risk of

different cancers including

cervical, ovarian, vaginal and

vulvar cancers.

Make healthy

choices.

It’s important to maintain a

healthy weight, be active and eat

a healthy diet consisting of fruit,

vegetables, lean proteins and

whole grains.

Share your family

history with your

doctor.

Genetic testing is now available

to see if you carry a BRCA1 or

BRCA2 mutation, which could

put you in a high-risk category

for ovarian and breast cancer. If

you carry a genetic mutation

associated to Lynch Syndrome,

a heredity condition that

increases your risk of colon

cancer, ovarian cancer, uterine

cancer, etc.

Contact your doctor

if you notice any of

these symptoms.

Abnormal vaginal

bleeding or discharge

Pelvic pain or

pressure

Abdominal or back

pain

Bloating

Changes in bathroom

habits (increased

urination, constipation,

diarrhea)

Itching or burning of

the vulva

Changes in vulva

color or skin (rash,

sores, warts, ulcers).

nfcr.org/

chemotherapy can reduce the risk of

metastatic tumors.

A collaboration of UK and Chinese

researchers has unlocked the secrets that

enable the medicinal herb to produce cancer

fighting compounds. The researchers used

DNA sequencing technology to assemble

the genomic sequence of skullcap. This gave

them the genetic information – a

microevolutionary history – required to

identify how the plant produces the

compound scutebarbatine A, which acts

against a range of cancer cells.

A new sustainable source for a

promising cancer killer

Tabernaemontana corymbosa produces a

natural cancer-killing molecule.

Normally, you’d have to travel all the way to

Malaysia to find the Tabernaemontana

corymbosa. Instead, CSHL chemists have

recreated this cancer killer in the lab using

sustainable chemistry techniques.

SKULLCAP

Image credit: Herbzest

https://www.herbazest.com/herbs/skullcap

TABERNAEMONTANA CORYMBOSA

Image credi: https://nysp-runner-

plants.blogspot.com/2011/04/tabernaemontana.html

New global funding opportunity for

Cancer Research

The National Cancer Institute (NCI), part

of the National Institutes of Health, and

Cancer Research UK have announced nine

new research challenges aimed at tackling

some of the most profound problems in

cancer research. The global funding

opportunity is part of the Cancer Grand

Challenges program, an initiative launched

by NCI and Cancer Research UK in 2020.

The research initiative aims to inspire bold

new ideas that have the greatest potential

for advancing cancer research and

improving outcomes for people affected by

cancer. The new round of challenges,

announced March 8, 2023, during the

Cancer Grand Challenges Annual Scientific

Summit in London, is open until June 22,

2023.

WHO-AFRO: Early detection remains

key in cervical cancer elimination

According to an article published by the

regional office in Africa for the World Health

Organization (WHO AFRO), cervical cancer

is preventable and treatable when detected

early, yet it remains the leading cause of

deaths amongst women in Africa. Nineteen

(19) out of 20 countries with the highest

burden of cervical cancer are in the African

region. In many parts of Africa, women are

presenting with advanced cervical cancer

due to limited access to cancer screening

services, limited diagnostic facilities, poor

health seeking behaviours mainly due to

myths and misconceptions in communities

on cervical cancer and cancer generally.

First African-produced cancer tests

to slash costs and waiting times

Moroccan-manufactured tests for breast

cancer and leukaemia is an important step in

ending the continent’s reliance on imported

pharmaceuticals. Most of the diagnostic kits

for cancer and other diseases in Africa are

expensive imports from outside the

continent, usually from Europe and the US.

The price of the kit can be double that of

what it would cost to manufacture it locally.

It is also a long process. It can take weeks or

months for the kits to arrive.

Page 4

Cancer is a leading

cause of premature

death in every

country in the world

But many of these

deaths can be

prevented

Cancer News: Africa

The cancer burden is

expected to nearly

double in sub-Saharan

Africa during the next

20 years as a result of

population growth and

ageing, reaching 1.5

million new cases and

1 million deaths

by 2040.

To overcome this

mounting challenge,

each country in sub-

Saharan Africa needs

to implement a cancer

control programme as

part of national health

planning and to have

at its disposal routine

surveillance systems

capable of monitoring

progress in the

delivery of specific

interventions.

IARC/WHO PRESS

RELEASE

10 May 2022

A new report from the

Union for International

Cancer Control (UICC)

provides insights into

the current situation of

the cervical cancer

burden in Africa, as

well as

recommendations to

improve access to care

and meet the cervical

cancer elimination

targets set by World

Health Organization

(WHO).

“Elimination” means

that

a country records fewer

than four cases of

cervical cancer for

100,000 people; in

Sub-Saharan Africa,

incidence rates are

currently more than ten

times higher.

The price of the kit can be double that of

what it would cost to manufacture it locally.

It is also a long process. It can take weeks or

months for the kits to arrive.

The current situation of cancer

care in Africa?

Cancer care in Africa has greatly improved

over the last 10 years. By 2017, 71% of

African countries, up from 46% in 2013, had

operational national cancer control

programmes, and the oncology workforce

has increased steadily. However, care and

services vary widely, sometimes within the

same country or region – from

offering state-of-the-art care to basic

services that can be hard to access. Many

patients in Africa are diagnosed with

advanced cancers and do not complete their

care. There are several reasons for this, cost

being the main one: patients frequently must

pay out of pocket to access care, incurring

expenses that can be financially catastrophic.

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Lifestyle changes may prevent nearly

half of the world’s cancer deaths

Recent comprehensive global study

investigated cancer cases that were

attributable to modifiable risk factors. It

found that nearly half of cancer deaths

worldwide, 44.4 percent, may have been

avoidable if the victims had paid attention to

factors that raised cancer risk and made

lifestyle changes to reduce those risks.

Adherence to healthy lifestyle

found to cut breast cancer recur-

rence/mortality

Strong adherence to cancer prevention

lifestyle recommendations is associated with

reductions in disease recurrence and

mortality among patients with high-risk

breast cancer, according to a study

Natural Sources of Selenium as

Functional Food Products for

Chemoprevention

In recent years, the chemopreventive effect

of diet has focused on selenium (Se), and

most epidemiological studies and clinical

trials support the protective role of Se

against cancer development. However, high

doses of Se supplements must be consumed

for an anti-cancer effect. The multi-centre,

double-blind, randomised, placebo-controlled

cancer prevention trial by Clark et al.

reported that supplementation of 200 µg of

Se per day can reduce the incidence of and

mortality from carcinomas.

How Do Diet and Exercise Help

Prevent Cancer?

According to the American Association for

Cancer Research (AACR) Cancer Progress

Report 2022, 15 types of cancer have been

linked to being overweight or obese, while

several other types have been associated with

physical inactivity. Many people know what

they should do to reduce cancer risk – maintain

a healthy weight, get regular exercise, limit

alcohol, and avoid tobacco. But it’s not always

clear to the general public why or how these

behaviors affect cancer risk.

HEALTH AND LIFESTYLE

Make whole grains, vegetables,

fruits and pulses (legumes) such as

beans and lentils a major part of

your normal diet

Scientific evidence shows that eating mostly

plant-based foods — whole grains, vegetables,

fruits, and beans – plays a big role in

preventing cancer and contributing to a

healthier life.

Benefits of good nutrition during

cancer treatment

Good nutrition is especially important if you

have cancer because both the illness and its

treatments can change the way you

eat. They can also affect the way your body

tolerates certain foods and uses nutrients.

During cancer treatment you might need to

change your diet to help build up your

strength and withstand the effects of the

cancer and its treatment. This may mean

eating things that aren’t normally recomm-

ended when you are in good health.

Page 5

Many people associate

grapefruit with dieting to

lose weight.

But research suggests any

weight loss help that

grapefruit provides is not

necessarily different than

what you get from any

other food that provides

low calories in a satisfying

portion. Regardless,

grapefruit has plenty to

offer beyond any

connection to weight

management due to the

cancer-protective

potential of its nutrients

and phytocompounds.

AICR

Image credit: freePNGimg

https://freepngimg.com/png/154448-

photos-grapefruit-half-free-clipart-hd

According to researchers,

cooking sweet corn boosts its

ability to fight cancer and heart

disease by freeing healthful

compounds

There is a notion that processed fruits

and vegetables have a lower nutritional

value than fresh produce. Those original

notions seem to be false, as cooked sweet

corn retains its antioxidant activity,

despite the loss of vitamin C.

In addition to its antioxidant benefits,

cooked sweet corn unleashes a phenolic

compound called ferulic acid, which

provides health benefits, such as battling

cancer.

Image credit: freePNGimg

https://freepngimg.com/food/corn

The COVID-19

pandemic is not over.

Never

forget this practice!

It is necessary

for your health

now and always.

Do it often.

The best for you is to

keep safe for yourself

and for us all.

Please do visit

our Fundraising

Webpage

For our Women

Cancer Survivors

YOUR GENEROSITY IS

HIGHLY APPRECIATED

CLICK HERE

FWHPWI

Current Project Groups

Research group

Education, Health and

Wellness group

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Support group

Cancer survivors group

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Carrots have long been in the public eye as an excellent way to support eye health but are now gaining

popularity among researchers as a cancer-fighting vegetable.

Many studies suggest that carrots and other non-starchy vegetables decrease one’s risk vegetables

decreases one’s risk of aero digestive

cancers, which include cancers of

the mouth, pharynx, larynx,

esophageal, lung, stomach, and colon.

Eating one carrot per day will

add a significant amount of

fiber and vitamin K to one’s diet.

Image credit: freePNGimg

https://freepngimg.com/png/10194-carrot-png